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Reduced solvent consumption by 57% in peptide solid phase synthesis

Customer Success Story from Polypeptide Group

"During our cooperation with Ypso -Facto, by associating our respective expertises , predictive simulation and experiments, we managed reducing by 57 % the solvent use for resin washing during SPPS ." Olivier LUDEMANN-...

Oligonucleotides & Peptides

Peptide chemistry: in-silico development tools for an efficient process design

ABSTRACT This article highlights a new way of thinking for the optimization of Peptide Synthesis. The concept is based on numerical tools to assist the peptide chemists for the choice of the manufacturing route. Process development can be shortened...

Advanced SPPS

Discussion on the challenge of large-scale peptide synthesis on solid supports

"Solid-Phase Peptide Synthesis (SPPS) is well established and routinely applied on efficient automatic synthesisers, which are available at laboratory scale. However, manufacturing peptides at industrial scale remains a major challenge, considering...