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Results found for your search on the term "Small molecules"
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Small molecules - Neutraceuticals - Antibodies - Antibiotics - Cosmetics - Enzymes - Oligonucleotides - Peptides - Proteins
Case studies & Application Notes
Case Study: Increasing yield and safety of a nitration process
Predictive simulations coupling mass & heat transfer
Challenge
40-year old nitration process for the production of an Active Pharmaceutical Ingredient
Highly complex process with low selectivity
Need to enhance competitiveness and improve safety
Methods...
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Case studies & Application Notes
Case Study: Debottlenecking of an esterification process
Development of a mechanistic model accounting for phase equilibria (G/L/S)
Challenge
Established process (> 40 years) for the production of an ester
Debottlenecking
Improving economics (OpEx) while minimizing investment
Methods
Identification of the reaction pathway thanks...
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Case studies & Application Notes
Case Study: Improving an industrial fermentation
Challenge
Scale-up of a industrial fermentation process
Need to improve productivity and process stability
Methods
Establishment of mass balances, calculations of yields and Oxygen Uptake Rates
...
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Webinars
Crystallization of polymorphs: advanced process monitoring, data analysis and mechanistic modeling for improved process understanding and optimization
Presented by Lucrèce Nicoud from Ypso-Facto and Richard Becker and Joe Oliva from Blaze Metrics
Many active pharmaceutical ingredients are known to crystallize in different polymorphic forms; a phenomenon that greatly impacts solubility, bioavailability, color, shape, filterability and tabletability. It is key to produce the targeted polymorph...
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Webinars
Deuterium in the 21st century, use in medicinal chemistry and synthetic methods.
Presented by Thomas Jennequin
Ninety years after its discovery, Deuterium is in the spotlights. Since the beginning of the 21 st century, a number of biotechnology companies have successfully explored its potential in drug candidates and generated intellectual property. This approach...
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Publications
Innovative organic chemistry: a differentiating driver for CMOs
A methodological approach to develop technical competitive advantages
ABSTRACT:
The fine chemicals segment is a field of continuous innovation with regards to new molecular structures in which Contract Manufacturing Organizations (CMOs) play a major role, in particular for the commercial-scale production of organic...
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