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Results found for your search on the term "Upstream"
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Small molecules - Neutraceuticals - Antibodies - Antibiotics - Cosmetics - Enzymes - Oligonucleotides - Peptides - Proteins
Publications
Bioprocess Simulation: Why the Industry Needs To Embrace Engineering Rather Than Empirical Approaches?
By Roger-Marc Nicoud in Bioprocess International
In 1903, the Wright brothers built the first functioning airplane, and botanist Mikhail Tsvet became the first scientist to use chromatography to separate components of a solution (carotene pigments, in his case).
Now, 120 years later, new airplanes...
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Case studies & Application Notes
Case Study: Improving an industrial fermentation
Challenge
Scale-up of a industrial fermentation process
Need to improve productivity and process stability
Methods
Establishment of mass balances, calculations of yields and Oxygen Uptake Rates
...
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Publications
CALIPSO: revolutionizing the management of bioproduction processes in healthcare
Paris (France) – September 16th, 2021 – Sanofi, Capgemini, Ypso-Facto, GPC Bio, CEA, CentralSupelec announce the launch of the project CALIPSO !
A structuring R&D project for French medical research, financed and coordinated by a consortium of high-profile industrial and public actors.
An essential mobilisation to accelerate access to new treatments at an acceptable cost, to ensure...
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Publications
Advanced SPPS
Discussion on the challenge of large-scale peptide synthesis on solid supports
"Solid-Phase Peptide Synthesis (SPPS) is well established and routinely applied on efficient automatic synthesisers, which are available at laboratory scale. However, manufacturing peptides at industrial scale remains a major challenge, considering...
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