Oligonucleotides & Peptides
Peptide chemistry: in-silico development tools for an efficient process design
Olivier Ludemann-Hombourger of PolyPeptide Laboratories and N. Petitjean of Ypso-Facto
ABSTRACT
This article highlights a new way of thinking for the optimization of Peptide Synthesis. The concept is based on numerical tools to assist the peptide chemists for the choice of the manufacturing route. Process development can be shortened without compromising on process performance and robustness, through the development of unique predictive tools and the use of numerical models to better understand the reaction mechanisms.
Read the full article in Chemistry Today