Contact us for a demo Follow us:
Continuous Biopharmaceutical Processes
Chromatography, Bioconjugation, and Protein Stability
David Pfister, Lucrèce Nicoud, Massimo Morbidelli
ABSTRACT: This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation...
Designing Robust Chromatographic Processes with a Proven Predictive Approach
Webinar by David Pfister
Preparative chromatography is a versatile purification technique used in various industrial sectors including petrochemistry, sugar production, pharmaceutical and fine chemistry, to name only a few. While this technology is often considered complex, expensive and sometimes not scalable, industrial success...
Designing affinity chromatographic processes for the capture of antibodies
Part I: A simplified approach
D. Pfister, L. David, M. Holzer, R.-M. Nicoud*
ABSTRACT Protein A affinity chromatography is a standard technique for the purification of therapeutic antibodies. Recently, multi-column chromatographic processes have emerged to turn classical capture processes into more efficient and continuous systems. The design of such chromatographic...
Comparing multi-column chromatographic processes for purifying monosaccharides
Part I: A simplifed approach
Laurent David, Jay Yun, Roger-Marc Nicoud*
ABSTRACT This work proposes a methodology for comparing different multi-column chromatographic processes (SMB, ISMB, SSMB) for purifying monosaccharides. The first step of the methodology consists in determining the flow rates associated with the different processes assuming that the columns are...
Innovative organic chemistry: a differentiating driver for CMOs
A methodological approach to develop technical competitive advantages
Marc-Olivier Simon,* Roger-Marc Nicoud
ABSTRACT: The fine chemicals segment is a field of continuous innovation with regards to new molecular structures in which Contract Manufacturing Organizations (CMOs) play a major role, in particular for the commercial-scale production of organic molecules. To face constant international competition...
Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.
Download
© Ypso-Facto 2014 - Powered by Ealys | Legal Information