BioProcess International Europe
Vienna (Austria), 2-5 April 2019
Ypso-Facto will be at BPI Europe in Vienna.
Come and hear the lecture by H. Osuna on 2nd April 2019:
Modeling and simulation of ion-exchange in bio-processes
– illustrations from industrial biotech to biopharma -
From a modeling point of view, ion-exchange is quite often described with classical adsorption isotherms as an approximation. Yet, there are also numerous examples demonstrating the limits of this approach.
In industrial biotech, the complexity of ion exchange phenomena has been modeled and fairly predicted. However, as molecules in biopharma represent a higher degree of complexity, they challenge the rigorous description of ion exchange phenomena involved in their isolation. We will show how to deal with complexity of molecules and ion exchange to bring on hand modeling and consequently a rigorous and competitive design of industrial biopharma processes.