- November 28, 2023
Mechanistic modeling completely replaces experiments: Myth or Fact?
Myth…for now A mechanistic model relies on first principles based on physico-chemical phenomena and requires estimating a number of model parameters specific to the case under investigation. The evaluation of model parameters is typically done based on a set of well targeted experiments. While...
- October 26, 2023
Doubled productivity of a multi-column ion exchange chromatographic process with increased purity
About the optimization of a multi-column Ion Exchange system : « In combination with AKBM “user-knowledge” and intuition, Ypso-Facto used experimental laboratory- and production-data and made simulation-models with the software “Ypso-Ionic”. With this GPX approach, Ypso-Facto...
- October 25, 2023
Three Benefits of Mechanistic Modeling For Chromatographic Process Development
Optimizing chromatographic processes can be achieved by employing mechanistic modeling, with the following benefits: Increase Process Understanding Get to the core of chromatography with mechanistic modeling. The combination of well targeted experiments with mechanistic simulations...
- September 12, 2023
Reduced solvent consumption by 57% in peptide solid phase synthesis
"During our cooperation with Ypso -Facto, by associating our respective expertises , predictive simulation and experiments, we managed reducing by 57 % the solvent use for resin washing during SPPS ." Olivier LUDEMANN- HOMBOURGER, Director Global - Innovation & Technology...
- June 12, 2023
Comparison of single and multi-column processes with mechanistic simulation
Multicolumn Chromatography is a strong possible alternative to single-column chromatography for improving process performances. Mechanistic simulations can be used to investigate several process options and quantify the impact on key performance indicators, thus providing a platform to make informed...
- May 08, 2023
Modeling: Mechanistic or Statistical ? Part 2 : Making a choice
Interested by knowing the differences between statistical and mechanistic approach? Click here to access part 1 of the article "Modeling : Mechanistic vs Statistical ? Part 1 : Modeling expectations" All modeling approaches need to be fed with experimental data to identify...
- March 13, 2023
Modeling: Mechanistic or Statistical ? Part 1 : Modeling expectations
Digital tools are used for well-known applications in our everyday life: energy production, navigation, drugs development, weather prediction, diseases detection. They are useful because they allow predicting: weather, illness, position and direction, conditions for minimizing energy consumption....
- February 02, 2023
How to easily extract relevant information and KPIs from your experimental data ?
Your data is one of your most valuable resources. But without a tool to exploit them in a structured way, you miss information that allow you to improve efficiency, increase productivity or decrease the experimental work burden. This is why we have developed Ypso-Ionic ® , which allows...
- January 12, 2023
Ensure reliable tech transfer thanks to comprehensive and structured data
Ypso-ionic® is a software solution for designing chromatographic processes . Compared to a classical ELN, Ypso-Ionic allows to describe, store and share your experimental data in a standardized, contextualized and rational manner across all users. Ypso-Ionic’s proprietary Y|F Data format...
Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.